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Before initiating amphotericin B for a fungal infection, which laboratory value should a nurse report to the provider?

  1. BUN 55 mg/dL

  2. Hemoglobin 12 g/dL

  3. WBC count 7,000/uL

  4. Platelet count 250,000/uL

The correct answer is: BUN 55 mg/dL

Before initiating amphotericin B for a fungal infection, a nurse should report a high blood urea nitrogen (BUN) level of 55 mg/dL to the healthcare provider. Amphotericin B can be nephrotoxic, which means it can cause kidney damage. Monitoring the BUN level is essential because an elevated BUN may indicate impaired kidney function, which would contraindicate the use of amphotericin B as it can further worsen kidney function. The other laboratory values provided in the question (Hemoglobin, WBC count, and Platelet count) are within normal limits and do not directly relate to the potential nephrotoxic effects of amphotericin B.