What effect do corticosteroids have on the immune system?

Corticosteroids are a class of medications that have a profound effect on the immune system, primarily by suppressing immune responses. They achieve this by inhibiting various immune system functions, which include the reduction of inflammatory mediator release, decreasing the activation and proliferation of lymphocytes (particularly T-cells), and inhibiting the migration of white blood cells to sites of inflammation. This suppression is beneficial in treating conditions where the immune system is overactive, such as autoimmune diseases, allergies, and certain inflammatory conditions.

The use of corticosteroids in medical treatment takes advantage of their ability to control excessive immune responses and inflammation, leading to a decrease in symptoms associated with these conditions. Therefore, their primary role in the context of the immune system is one of suppression, which is a key mechanism underlying their therapeutic effectiveness.

In contrast, some options suggest effects like enhancing immune responses, promoting inflammation, or stimulating antibody production, none of which align with the pharmacological action of corticosteroids. Rather, corticosteroids are known for their immunosuppressive properties, making them crucial in managing diseases where immune regulation is necessary.