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Which indicates a therapeutic response to epinephrine given for angioedema after a first dose of losartan?

  1. Decreased appetite

  2. Respirations are unlabored

  3. Increased heart rate

  4. Decreased urination

The correct answer is: Respirations are unlabored

Losartan is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure. Angioedema is a known potential side effect of ACE inhibitors. Epinephrine is a treatment for angioedema because it acts as a potent vasoconstrictor and bronchodilator. In this scenario, after the administration of epinephrine for angioedema following the first dose of losartan, a therapeutic response would be indicated by unlabored respirations. This is because epinephrine helps to alleviate airway constriction, allowing for easier breathing in cases of angioedema. Therefore, the correct answer is B. Options A, C, and D are not associated with the therapeutic response to epinephrine in the context of treating angioedema.