Pharmacology Proctored ATI Practice Exam

Which of the following is an adverse effect of diphenhydramine that a nurse should mention to a client?

1. Sedation

2. Hypertension

3. Diarrhea

4. Weight gain

The correct answer is: Sedation

Diphenhydramine, also known as Benadryl, is an antihistamine medication commonly used to treat allergies and promote sleep. Its main side effect is sedation, which means it can make a person feel drowsy or sleepy. This is something that a nurse should mention to a client because it can affect their ability to perform daily activities or operate heavy machinery. Hypertension, which is high blood pressure, is not a side effect of diphenhydramine and can actually be treated with this medication. Diarrhea is also not a common side effect and if it does occur, it is usually temporary. Weight gain is not a known side effect of this medication either. Therefore, A is the correct answer as it is the only adverse effect that is associated with diphenhydramine.